Organ-sparing surgery of penile cancer: higher rate of local recurrence yet no impact on overall survival

Penile sparing surgery for penile cancer-does it affect survival?

PURPOSE Management of squamous cell carcinoma of the penis changed in recent decades in favor of penile sparing surgery. We assessed whether penile sparing therapies were increasingly applied in our penile squamous cell carcinoma cohort with time and whether penile sparing affected 5-year cancer specific survival. MATERIALS AND METHODS We reviewed the records of 1,000 patients treated between...

Current concepts of organ-sparing surgery in penile cancer

The report by Palminteri et al. on penis-preserving surgery (PPS) in various benign and malignant penile lesions is interesting. The authors describe their technique of the use of the split-thickness skin graft (STSG) for neo-glans reconstruction after glansectomy, partial penectomy and in patients in whom all the glanular skin is removed and replaced by STSG. They confirm the feasibility of op...

Primary penile cancer organ sparing treatment

INTRODUCTION Surgical treatment of penile cancer is usually associated with mutilation; alterations in self-esteem and body image; affecting sexual and urinary functions; and declined health-related quality of life. Recently, organ sparing treatment has appeared and led to limiting these complications. MATERIAL AND METHODS An extensive review of the literature concerning penile-preserving str...

Surgery for colorectal liver metastases: the impact of resection margins on recurrence and overall survival

BACKGROUND Several reports have presented conflicting results regarding the association between resection margins (RMs) and outcome after surgery for colorectal liver metastases (CLM), especially in the era of modern chemotherapy. The purpose of this study was to evaluate the impact of RMs on overall survival (OS), time to recurrence (TTR) and local recurrence (LR) status, particularly for pati...

Organ-sparing reconstructive surgery in penile cancer: initial experiences at two